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Filtered Search Results
Medchemexpress LLC VE-821 | 1232410-49-9 | 99.7% | 368.41 | 50 MG
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VE-821 is a potent ATP-competitive inhibitor of ATR, with Ki/IC50 values of 13 nM/26 nM. It demonstrates excellent selectivity for ATR, showing minimal cross-reactivity against related PIKKs such as ATM, DNA-PK, mTOR, and PI3Kγ.
- Shows minimal cross-reactivity against related PIKKs ATM, DNA-PK, mTOR, and PI3Kγ
- Significantly enhances the sensitivity of PSN-1, MiaPaCa-2, and primary PancM pancreatic cancer cells to radiation and Gemcitabine
- ATR inhibition by VE-821 leads to inhibition of radiation-induced G2/M arrest in cancer cells
- Inhibits phosphorylation of Chk1 (Ser 345) in PSN-1 and MiaPaCa-2 cells after treatment with Gemcitabine, radiation, or both
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Medchemexpress LLC 1,4,7,10-tetraazacyclododecane-1,4,7-tris(acetic acid)-10-(3-butynylacetamide) | 2125661-62-1 | MFCD35160514 | 97.0% | 455.51 | C20H33N5O7 | 5mg
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Butyne-DOTAis a bifunctional chelator (Bifunctional Chelator BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting Butyne-DOTA can be used for conjugation of peptides and radionuclides
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Medchemexpress LLC 5-phenyl-1-pentyne (pent-4-ynylbenzene) | 1823-14-9 | MFCD00039813 | 98.0% | 144.21 g·mol⁻¹ | C11H12 | 500 MG
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5-Phenyl-1-pentyne is a terminal alkyne used as a building block and intermediate in organic synthesis and medicinal chemistry research. It is supplied as a high-purity small-molecule suitable for laboratory applications.
- High purity: 98.0%.
- CAS number: 1823-14-9.
- Chemical formula C11H12; molecular weight 144.21 g·mol⁻¹.
- Provided in milligram and gram pack sizes for research use.
- SMILES identifier available for structure confirmation.
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Medchemexpress LLC Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate | 1049004-32-1 | 280.17 | 5 G
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Bpin-Cyclohexene-COOEt, also known as Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate, is a PROTAC linker belonging to the PEG class. It is designed for use in the synthesis of PROTAC molecules. This compound is a colorless to light yellow liquid.
- Intended for research use only.
- Unstable in solutions, requiring freshly prepared solutions for optimal use.
- Molecular weight of 280.17.
- Purity of 97.0%.
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Medchemexpress LLC Ethyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enyl)acetate | 1166829-70-4 | >97.0% | 294.19 | C16H27BO4 | 500 MG
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Bpin-Cyclohexene-C-COOEt is a boron-pinacol substituted cyclohexene ethyl acetate used as a PROTAC linker in medicinal chemistry and targeted protein degradation research. The compound is supplied for research use only and is reported to have high purity and defined molecular characteristics.
- used as a PROtac linker in targeted protein degradation research.
- molecular formula: C16H27BO4.
- molecular weight: 294.19 g/mol.
- high purity (>97.0%).
- suitable for synthesis of SMARCA2/4 degrader scaffolds and related intermediates.
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Medchemexpress LLC Bay 65-1942 hydrochloride | 600734-06-3 | 99.4% | C22H26ClN3O4 | 25 MG
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Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor, appearing as a white to off-white solid. It has demonstrated efficacy in reducing left ventricular infarct size and attenuating CK-MB levels in vitro. In vivo studies show synergistic inhibition of cell viability when combined with AZD6244, and it induces caspase 3/7 activation, making it a valuable tool for research in cancer, inflammation, and immune system diseases.
- ATP-competitive and selective IKKβ inhibitor
- White to off-white solid appearance
- Soluble in DMSO (50 mg/mL) and H2O (2.17 mg/mL)
- Inhibits IKKβ activity
- Decreases left ventricular infarct size in vitro
- Attenuates CK-MB levels in vitro
- Demonstrates synergistic inhibition of cell viability with AZD6244 in vivo
- Induces caspase 3/7 activation in vivo
- Relevant for research in cancer, inflammation, and immune system diseases
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eMolecules 7-Tetradecene | 10374-74-0 | MFCD00009550 | 1g
Oakwood Chemicals | 7-Tetradecene | 1g | 480151123 | 099796 | | 10374-74-0 | MFCD00009550 | 196.378 | C14H28
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Medchemexpress LLC 1-dodecene | 112-41-4 | MFCD00008961 | 96.9% | 168.32 g/mol | C12H24 | 100 G
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1-Dodecene is a linear alpha-olefin (C12H24) used as a reagent and chemical intermediate in organic synthesis and in the manufacture of surfactants and lubricants. It is supplied as a colorless to light yellow liquid with a GC-reported purity of 96.9% and a molecular weight of 168.32 g/mol.
- Linear alpha-olefin reagent for organic synthesis and intermediates.
- High GC purity (96.9%).
- Colorless to light yellow liquid, easy to handle in standard laboratory conditions.
- Molecular formula C12H24; molecular weight 168.32 g/mol.
- Suitable for use in surfactant and lubricant production.
- Certificate of analysis and safety data sheet available for quality and safety verification.
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Medchemexpress LLC N-(4,6-dimethyl-2-pyridinyl)-4-[[4-(trifluoromethyl)phenyl]methyl]piperazine-1-carbothioamide | 1916571-90-8 | 99.7% | 408.48 g/mol | C20H23F3N4S | 1 ML
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NCT-503 is a small-molecule inhibitor of phosphoglycerate dehydrogenase (PHGDH) used in biochemical and cellular research. It exhibits an in vitro IC50 of 2.5 μM and is provided as either a solid or a ready-to-use 10 mM solution in DMSO for cell-based and biochemical assays.
- Inhibits PHGDH with an IC50 of 2.5 μM.
- High purity (99.69%).
- Molecular weight 408.48 g/mol.
- Available as a 10 mM DMSO solution (1 mL) and multiple solid sizes.
- Soluble in DMSO (50 mg/mL) and ethanol (13.33 mg/mL) with recommended handling.
- Recommended storage: powder at -20°C (long term) or 4°C; solutions at -80°C or -20°C.
- Intended for research use only.
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Cayman Chemical cIs-PetroselInIc AcId 50mg
A monounsaturated fatty acid and isomer of oleic acid; major component of plant lipids; rats fed a diet containing it have a reduction in arachidonic acid levels and an increase in linoleic acid levels in the heart, liver, and blood; has been used in a composite membrane to study plant uptake; has been used in the synthesis of new biosurfactants (sophorolipids)
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Aqua Solutions 1-OCTENE IN SOLVENT ISOPAR E
Aqua Solutions 30% w/w 1-octene in Solvent (Isopar E) (600G)
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Aqua Solutions 1-OCTENE IN SOLVENT ISOPAR E
Aqua Solutions 20% w/w 1-octene in Solvent (Isopar E) (600G)
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Cambridge Isotope Laboratories Methyl triclosan (2 4 4-trichloro-2-methoxy- diphenyl ether) (unlabeled) 100 ug/mL in nonane 1 2 mL
Methyl triclosan (2 4 4-trichloro-2-methoxy- diphenyl ether) (unlabeled) 100 ug/mL in nonane 1 2 mL
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Aobchem 4-Methyl-1-phenylpent-2-yne-1 4-diol | 95% | CAS 5111-41-1 | C12H14O2 | 5g
4-Methyl-1-phenylpent-2-yne-1 4-diol | 95% | CAS 5111-41-1 | C12H14O2 | 5g
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eMolecules 501-65-5 | Diphenylacetylene | MFCD00004786 | 25g
Ambeed | Diphenylacetylene | 25g | 569094816 | A360795 | 501-65-5 | MFCD00004786 | 178.234 | C14H10
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